论文、课题、专利与专家共识

Glioma-induced neural functional remodeling in the hand motor cortex: precise mapping with ECoG grids during awake craniotomy 杨渊：通讯作者 作者顺序：Tao Chang; Yihan Wu; Yuxin Quan; Siliang Chen; Jiawei Liao; Wenyu Zhao; Yu Li; Yuan Fang; Yixuan Zong; Yanhui Liu; Ning Jiang; Qing Mao; Jiayuan He; Yuan Yang International Journal of Surgery. 2025;111(4):2849-2861. DOI: 10.1097/JS9.0000000000002277; PMID: 39903573.

以高密度 ECoG 网格与唤醒手术场景刻画运动皮层功能重塑。

Analysis of electrocorticographic signal activity characteristics in motor cortex glioma 中文题名：运动区胶质瘤皮质脑电信号活动度特征分析；杨渊：通讯作者 作者顺序：Wen-yu Zhao; Yan-hui Liu; Qing Mao; Ning Jiang; Jia-yuan He; Yuan Yang Chinese Journal of Contemporary Neurology and Neurosurgery. 2025;25(7):602-607. DOI: 10.3969/j.issn.1672-6731.2025.07.006; PMID: 未见 PubMed 收录.

围绕运动区胶质瘤皮层脑电活动、功能区定位和术中电生理证据展开。

Passive Intraoperative Tumor Mapping Using Electrocorticography World BCI Awards · 2024 Nominee

将术中被动 ECoG 映射推向脑肿瘤精准外科场景。

Surgical treatment and survival outcome of patients with adult thalamic glioma: a single institution experience of 8 years Yuan Yang：共同第一作者 作者顺序：Xiaodong Niu; Tianwei Wang; Xingwang Zhou; Yuan Yang; Xiang Wang; Haodongfang Zhang; Ni Chen; Qiang Yue; Feng Wang; Yuekang Zhang; Yanhui Liu; Qing Mao Journal of Neuro-Oncology. 2020;147(2):377-386. DOI: 10.1007/s11060-020-03430-x; PMID: 32157551.

单中心队列总结成人丘脑胶质瘤手术治疗与生存结局。

A prognostic nomogram for patients with newly diagnosed adult thalamic glioma in a surgical cohort 杨渊：共一作者 作者顺序：Xiaodong Niu; Yuan Yang; Xingwang Zhou; Haodongfang Zhang; Yuekang Zhang; Yanhui Liu; Qing Mao Neuro-Oncology. 2021;23(2):337-338. DOI: 10.1093/neuonc/noaa268; PMID: 33244611.

建立成人丘脑胶质瘤预后列线图，用于风险分层与临床决策支持。

成人丘脑胶质瘤手术治疗中国专家共识 临床神经外科杂志 · 2022 · 执笔参与

推动复杂深部脑肿瘤诊疗经验的系统化和规范化。

The impact of maximized resection and standardized systemic therapy on overall survival in adult patients with thalamic gliomas 杨渊：通讯作者 作者顺序：Junjie Wang; Xiaodong Niu; Tao Chang; Yuxin Quan; Lloyd Mulenga Mwibwe; Yanhui Liu; Xiang Wang; Yuan Yang; Qing Mao Frontiers in Oncology. 2025;15:1681695. DOI: 10.3389/fonc.2025.1681695; PMID: 41244892.

评估最大范围切除和标准化系统治疗对成人丘脑胶质瘤总生存的影响。

Multi-Omics Analysis Reveals Novel Subtypes and Driver Genes in Glioblastoma Yang Yuan：第一作者 作者顺序：Yang Yuan; Pan Qi; Wang Xiang; Liu Yanhui; Li Yu; Mao Qing Frontiers in Genetics. 2020;11:565341. DOI: 10.3389/fgene.2020.565341; PMID: 33324446.

围绕胶质母细胞瘤多组学分型、驱动基因和预后线索构建分析框架。

Weighted correlation network analysis identifies susceptibility loci Cancer Medicine · 2022 · 通讯作者

围绕低级别胶质瘤易感位点和网络关联开展分子机制研究。

A novel score system based on arginine metabolism-related genes to predict prognosis, characterize immune microenvironment, and forecast response to immunotherapy in IDH-wildtype glioblastoma 杨渊：通讯作者 作者顺序：Wentao Feng; Mingrong Zuo; Wenhao Li; Siliang Chen; Zhihao Wang; Yunbo Yuan; Yuan Yang; Yanhui Liu Frontiers in Pharmacology. 2023;14:1145828. DOI: 10.3389/fphar.2023.1145828; PMID: 37214463.

构建代谢相关评分，预测预后、免疫微环境和免疫治疗反应。

Variable screening and model construction for prognosis of elderly patients with lower-grade gliomas based on LASSO-Cox regression: a population-based cohort study 杨渊：通讯作者 作者顺序：Xiaodong Niu; Tao Chang; Yuekang Zhang; Yanhui Liu; Yuan Yang; Qing Mao Frontiers in Immunology. 2024;15:1447879. DOI: 10.3389/fimmu.2024.1447879; PMID: 39324140.

基于人群队列构建老年低级别胶质瘤预后模型。

基于高维脑电信号联合基因多组学分析揭示胶质瘤与神经元交互调控机制 国家自然科学基金 · 82573942 · 2026-2029 · 总题负责

围绕胶质瘤-神经元交互、脑电特征与分子机制开展交叉研究。

基于脑机接口的脑部手术辅助关键技术研究及应用 四川省科技厅 · 2025YFRG0006 · 2025-2028 · 总题负责

推动脑机接口辅助神经外科手术关键技术与临床应用。

一种基于被动运动诱发电位的脑功能区检测方法及系统 专利申请权转让 · 华科精准 · 2025

服务脑功能区检测、术中验证和设备转化路径。